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XTBG OpenIR  > 2012年后新成立研究组  > 期刊论文

title: Bamboo shoot fiber prevents obesity in mice by modulating the gut microbiota
author: Li, Xiufen;  Guo, Juan;  Ji, Kailong;  Zhang, Ping
Issued Date: 2016
Abstract: Dietary fiber has been shown to prevent high-fat diet induced obesity through modulating the gut microbiota; however, quality difference in fiber type is largely unknown. We performed a 6 week study on C57BL/6J mice fed a macronutrient matched high-fat diet with different fiber types including cellulose (HFC), bamboo shoot fiber (HFBS) and several other commonly consumed fibers. Our results showed that the HFBS group exhibited the lowest weight gain among all diet groups and had improved lipid profiles and glycemic control compared with the HFC group. As revealed by 16S rRNA gene sequencing, loss of diversity in the gut microbiota induced by the HFC diet was largely prevented by the HFBS diet. Moreover, compared with the HFC diet, the HFBS diet resulted in markedly increased relative abundance of Bacteroidetes and strong inhibition of Verrucomicrobia, two divisions strongly correlated with body weight. In conclusion, the present study provides evidence of a quality difference among different types of dietary fibers and shows that bamboo shoot fiber is the most effective in suppressing high-fat diet induced obesity. Our findings indicate that bamboo shoot fiber is a potential prebiotic fiber which modulates the gut microbiota and improves host metabolism.
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全文许可: Creative Commons 署名-非商业性使用-相同方式共享 3.0

Recommended Citation:
Li, Xiufen,Guo, Juan,Ji, Kailong,et al. Bamboo Shoot Fiber Prevents Obesity In Mice By Modulating The Gut Microbiota[J]. Scientific Reports,2016,6(32953).

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