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Drug evaluation: Eribulin, a simplified ketone analog of the tubulin inhibitor halichondrin B, for the potential treatment of cancer
Newman, S
2007
Source PublicationCURRENT OPINION IN INVESTIGATIONAL DRUGS
ISSN1472-4472
Volume8Issue:12Pages:1057-1066
AbstractEisai Co Ltd is developing eribulin, a simplified synthetic macrocyclic ketone analog of the tubulin inhibitor halichondrin B, for the potential treatment of cancer. Phase III trials are underway in the US and Europe for patients with breast cancer. Eribulin is currently in phase II trials for NSCLC and soft tissue sarcoma, and pancreatic, prostate, ovarian, fallopian tube, peritoneal and head and neck cancer, and phase I/II trials for urothelial cancers.
KeywordHuman Breast-cancer Multidrug-resistance Practical Synthesis Natural-products P-glycoprotein Solid Tumors In-vitro Expression Mechanism Segment
Language英语
Document Type期刊论文
Identifierhttp://ir.xtbg.org.cn/handle/353005/10248
Collection文献共享
Recommended Citation
GB/T 7714
Newman, S. Drug evaluation: Eribulin, a simplified ketone analog of the tubulin inhibitor halichondrin B, for the potential treatment of cancer[J]. CURRENT OPINION IN INVESTIGATIONAL DRUGS,2007,8(12):1057-1066.
APA Newman, S.(2007).Drug evaluation: Eribulin, a simplified ketone analog of the tubulin inhibitor halichondrin B, for the potential treatment of cancer.CURRENT OPINION IN INVESTIGATIONAL DRUGS,8(12),1057-1066.
MLA Newman, S."Drug evaluation: Eribulin, a simplified ketone analog of the tubulin inhibitor halichondrin B, for the potential treatment of cancer".CURRENT OPINION IN INVESTIGATIONAL DRUGS 8.12(2007):1057-1066.
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