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ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA
Hu, Xiang1; Chen, Wen1; Li, Jing; Huang, Shulan1; Xu, Xuling; Zhang, Xuan; Xiang, Shuanglin1; Liu, Changning
2018
Source PublicationDATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
ISSN1758-0463
IssuexPages:-
Abstract

There is emerging evidence showing that lncRNAs can be involved in various critical biological processes. Zebrafish is a fully developed model system being used in a variety of basic research and biomedical studies. Hence, it is an ideal model organism to study the functions and mechanisms of lncRNAs. Here, we constructed ZFLNC-a comprehensive database of zebrafish lncRNA that is dedicated to providing a zebrafishbased platform for deep exploration of zebrafish lncRNAs and their mammalian counterparts to the relevant academic communities. The main data resources of lncRNAs in this database come from the NCBI, Ensembl, NONCODE, zflncRNApedia and literature. We also obtained lncRNAs as a supplement by analysing RNA-Seq datasets from SRA database. With these IncRNAs, we further carried out expression profiling, co-expression network prediction, Gene Ontology (GO)/Kyoto Encyclopedia of Genes and Genomes (KEGG)/Online Mendelian Inheritance in Man (OMIM) annotation and conservation analysis. As far as we know, ZFLNC is the most comprehensive and well-annotated database for zebrafish lncRNA.

KeywordLong Noncoding Rnas Evolution Features Transcripts Mechanisms Expression Lincrnas Elements Network System
Subject AreaMathematical & Computational Biology
DOI10.1093/database/bay114
Indexed BySCI
Language英语
WOS IDWOS:000450962500001
Citation statistics
Document Type期刊论文
Identifierhttp://ir.xtbg.org.cn/handle/353005/11160
Collection2012年后新成立研究组
Affiliation1.Chinese Acad Sci, CAS Key Lab Trop Plant Resources & Sustainable Us, Xishuangbanna Trop Bot Garden, Kunming 650223, Yunnan, Peoples R China
2.Hunan Normal Univ, Sch Life Sci, State Key Lab Dev Biol Freshwater Fish, Changsha 410081, Hunan, Peoples R China
Recommended Citation
GB/T 7714
Hu, Xiang,Chen, Wen,Li, Jing,et al. ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA[J]. DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION,2018(x):-.
APA Hu, Xiang.,Chen, Wen.,Li, Jing.,Huang, Shulan.,Xu, Xuling.,...&Liu, Changning.(2018).ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA.DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION(x),-.
MLA Hu, Xiang,et al."ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA".DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION .x(2018):-.
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