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Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities
Cao, Dong-Hua; Sun, Peng; Liao, Shang-Gao; Gan, Li-She; Yang, Lin; Yao, Jian-Neng; Zhang, Zong-Yi; Li, Jin-Feng; Zheng, Xiao-Ling; Xiao, Yi-Dian; Xiao, Chun-Fen; Zhang, Ping; Hu, Hua-Bin; Xu, You-Kai
2019
Source PublicationPHYTOCHEMISTRY LETTERS
ISSN1874-3900
Volume29Issue:xPages:142-147
Abstract

Phytochemical investigation on the twigs and leaves of Trichilia sinensis led to the isolation of two previously undescribed limonoids (i.e., trichiliasinenoids D and E, 1 and 2), two previously undescribed phenolic acids (3 and 4), and one previously undescribed natural phenolic acid dimer (5), together with 11 known compounds (616). Their structures were elucidated by extensive spectroscopic analysis (IR, UV, HRESIMS, 1D and 2D NMR) and chemical techniques. The potential anti-inflammatory activities of all the compounds were evaluated in lipopolysaccharide-stimulated RAW 264.7 cells. Among these isolates, compounds 1, 2, 6, and 11-13 expressed weak NO inhibition. The antibacterial activities of all the compounds against bacteria were also tested in vitro. Compound 16 exhibited moderate antibacterial activities against Escherichia Coli.

KeywordGlycosides Limonoids Chemistry
Subject AreaPlant Sciences ; Pharmacology & Pharmacy
DOI10.1016/j.phytol.2018.11.020
Indexed BySCI
Language英语
WOS IDWOS:000456346200029
Citation statistics
Document Type期刊论文
Identifierhttp://ir.xtbg.org.cn/handle/353005/11208
Collection民族植物学研究组
Affiliation1.[Cao, Dong-Hua
2.Sun, Peng
3.Yang, Lin
4.Zhang, Zong-Yi
5.Li, Jin-Feng
6.Zheng, Xiao-Ling
7.Xiao, Chun-Fen
8.Zhang, Ping
9.Hu, Hua-Bin
10.Chinese Acad Sci, CAS Key Lab Trop Plant Resources & Sustainable Us, Xishuangbanna Trop Bot Garden, Menglun 666303, Peoples R China
11.[Cao, Dong-Hua
12.Sun, Peng
13.Yao, Jian-Neng
14.Zhang, Zong-Yi
15.Li, Jin-Feng
16.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
17.Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Guiyang 550025, Guizhou, Peoples R China
18.Guizhou Med Univ, Sch Pharm, Guiyang 550025, Guizhou, Peoples R China
19.Zhejiang Univ, Coll Pharmaceut Sci, Inst Modern Chinese Med, Hangzhou 310058, Zhejiang, Peoples R China
20.[Yao, Jian-Neng
21.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
22.Yunnan Univ, Sch Chem Sci & Technol, Key Lab Med Chem Nat Resource, Minist Educ, Kunming 650091, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Cao, Dong-Hua,Sun, Peng,Liao, Shang-Gao,et al. Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities[J]. PHYTOCHEMISTRY LETTERS,2019,29(x):142-147.
APA Cao, Dong-Hua.,Sun, Peng.,Liao, Shang-Gao.,Gan, Li-She.,Yang, Lin.,...&Xu, You-Kai.(2019).Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities.PHYTOCHEMISTRY LETTERS,29(x),142-147.
MLA Cao, Dong-Hua,et al."Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities".PHYTOCHEMISTRY LETTERS 29.x(2019):142-147.
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