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title: Cytotoxic limonoids from the leaves of Walsura robusta
author: Kai-Long Ji;  Xiao-Nian Li;  Shang-Gao Liao;  Hua-Bin Hu;  Ren Li;  You-Kai Xu
Issued Date: 2015
Abstract: Two new vilasinin limonoids, walsuronoids D–E (12), along with three known compounds (35) were isolated and identified from the leaves of Walsura robusta. Their structures were established based on extensive spectroscopic analysis. Compounds 12 showed potent cytotoxic activity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cancer cell lines, with IC50 values ranging from 2.7 to 4.5 μM. The absolute configuration of 3 was determined to be (24R, 25S)-cycloartane-3β,24,25,26-tetrol for the first time by using X-ray diffraction analysis.
Source: Phytochemistry Letters
Appears in Collections:民族植物学研究组_期刊论文

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Recommended Citation:
Kai-Long Ji,Xiao-Nian Li,Shang-Gao Liao,et al. Cytotoxic Limonoids From The Leaves Of Walsura Robusta[J]. Phytochemistry Letters,2015,15(X):53-56.

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