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title: New Benzamide Derivatives and NO Production Inhibitory Compounds from Limonia acidissima
author: Kim, Ki Hyun;  Lee, Il Kyun;  Kim, Kyung Ran;  Ha, Sang Keun;  Kim, Sun Yeou;  Lee, Kang Ro
Issued Date: 2009
Abstract: Three new benzamide derivatives, N-{[p-(3,7-dimethyl-6R,7-dihydroxy-4R-octadecanoyloxy-2-octenyloxy)phenyl]ethyl} benzamide (1), N-{[p(3,7-dimethyl-6R,7-dihydroxy-4R-9'"(E)-octadecenoyloxy-2-octenyloxy)phenyl]ethyl} benzamide (2), and N-{[p-(3,7-dimethyl-6R,7-epoxy-4R-9'"(E)-octadecenoyloxy-2-octenyloxy)phenyl]ethyl} benzamide (3), together with 10 known compounds (4-13), were isolated from the bark of Li-monia acidissima. The structures of these new compounds were determined through spectral analyses, including extensive 2D NMR data. Among the isolates, 13 alpha,14 beta,17 alpha-lanosta-7,9,24-triene-3 beta,16 alpha-diol (8), 4-methoxy-l-methyl-2 (1H)-quinolinone (10), and 13 alpha,14 beta,17 alpha-lanosta-7,24-diene-3 beta,11 beta,16 alpha-triol (13) potently inhibited nitric oxide (NO) production in microglia cells.
Related URLs: 10.1055/s-0029-1185512
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Recommended Citation:
Kim, Ki Hyun,Lee, Il Kyun,Kim, Kyung Ran,et al. New Benzamide Derivatives And No Production Inhibitory Compounds From Limonia Acidissima[J]. Planta Medica,2009,75(10):1146-1151.

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