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title: Cipacinoids A-D, Four Limonoids with Spirocyclic Skeletons from Cipadessa cinerascens
author: Yu, Jin-Hai;  Liu, Qun-Fang;  Sheng, Li;  Wang, Guo-Cai;  Li, Jia;  Yue, Jian-Min
Issued Date: 2016
Abstract: Four limonoids, cipacinoids A-D (1-4), with spirocyclic skeletons were isolated from Cipadessa cinerascens. It is particularly notable that compounds 1-3 had a 17S-configuration for the first time in the limonoid family. Their structures with absolute configurations were assigned by spectroscopic data, X-ray crystallography, and CD analysis. Compound 1 showed moderate protein tyrosine phosphatase 1B (PTP1B) inhibition.
Related URLs: 10.1021/acs.orglett.5b03487
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Recommended Citation:
Yu, Jin-Hai,Liu, Qun-Fang,Sheng, Li,et al. Cipacinoids A-d, Four Limonoids With Spirocyclic Skeletons From Cipadessa Cinerascens[J]. Organic Letters,2016,18(3):444-447.

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