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Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia
Zhang, Hua; Liu, Jia; Gan, Li-She; Dalal, Seema; Cassera, Maria B.; Yue, Jian-Min
2016
Source PublicationORGANIC & BIOMOLECULAR CHEMISTRY
ISSN1477-0520
Volume14Issue:3Pages:957-962
AbstractChemical investigation into the minor constituents of Aphanamixis grandifolia yielded three new diterpenoid dimers, aphadilactones E-G (1-3) featuring a new carbon skeleton. Their structures and absolute configurations were fully established by comprehensive spectroscopic data analysis and ECD calculation. Discovery of another two new dimers (4 and 5) suggested the structure of recently reported aphanamene A to be re-investigated. Compounds 1-5 showed moderate antimalarial activities with low micromolar IC50 values.
KeywordAphadilactones A-d Stem Barks Chemical-constituents Fruits Triterpenoids Derivatives Limonoids Ring
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.xtbg.org.cn/handle/353005/9800
Collection文献共享
Recommended Citation
GB/T 7714
Zhang, Hua,Liu, Jia,Gan, Li-She,et al. Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2016,14(3):957-962.
APA Zhang, Hua,Liu, Jia,Gan, Li-She,Dalal, Seema,Cassera, Maria B.,&Yue, Jian-Min.(2016).Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia.ORGANIC & BIOMOLECULAR CHEMISTRY,14(3),957-962.
MLA Zhang, Hua,et al."Antimalarial diterpenoid dimers of a new carbon skeleton from Aphanamixis grandifolia".ORGANIC & BIOMOLECULAR CHEMISTRY 14.3(2016):957-962.
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